Reconnecting after Quarantine
10-11 June 2021
PDF renditions of the PowerPoint presentations can be viewed and downloaded from this page by clicking the specific point on the program. The program itself can be viewed and downloaded by clicking here.
Program details of the EBF 7th YSS
| 10 June 2021 | |||
| 11:30 | 13:00 | Welcome at local sites – local site program as appropriate | |
| 13:00 | 13:10 | Welcome | |
| Philip Timmerman | |||
| 13:10 | 14:30 | Session 1: Achieving better sensitivity and selectivity | |
| Chair/Moderator/Questions: Connor/Mathias/Salvatore | |||
| 13:10 | 13:30 | Steven Schoemaker – PRA-HS | |
| Chiral derivatization for enhancing sensitivity and speed of the LC-MS/MS determination of the enantiomers of ibuprofen. | |||
| 13:30 | 13:50 | Claire Szuster – LGC | |
| The diasteromer double-peak dilemma | |||
| 13:50 | 14:10 | Marco Cirrincione – University of Bologna | |
| Enantiomeric separation of chiral synthetic opioids and metabolites in DBS by UHPLC-HRMS | |||
| 14:10 | 14:30 | Rosie Penford – GlaxoSmithKline | |
| The identification and development of a fit for purpose biomarker assay using the MSD platform | |||
| 14:45 | 15:15 | Parallel Session 2 | |
| Training Course: the basics of ADA in 30 minutes presenter: Salvatore Calogero, on behalf of the EBF |
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| 14:45 | 15:15 | Parallel Session 3 | |
| Training Course: the basics of LC-MS in 30 minutes presenter: Terrence Hetzel/Connor Walker, on behalf of the EBF |
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| 15:30 | 18:00 | Session 4: Miniaturisation and automation | |
| Chair/Moderator/Questions: Michele/Ian/Muriel | |||
| 15:30 | 15:50 | Liesl Heughebaert – University of Ghent | |
| Near-infrared-based hematocrit prediction of dried blood spots: an in-depth evaluation | |||
| 15:50 | 16:10 | Camilla Marasca – University of Bologna | |
| Haematic volumetric microsampling for TDM of patients under treatment with lurasidone | |||
| 16:10 | 16:30 | Bryan van den Broek – Sanquin | |
| Measuring antibodies in capillary blood: improvements by moving from dried blood spot to haematocrit independent micro-sampling | |||
| 16:30 | 16:40 | short break | |
| 16:40 | 17:00 | George Walters – LGC | |
| Automation vs Analyst: The Future of Bioanalysis | |||
| 17:00 | 17:20 | Sigrid Deprez – University of Ghent | |
| Fully Automated Dried Blood Spot-Based Therapeutic Drug Monitoring of Immunosuppressants | |||
| 17:20 | 17:40 | John Smeraglia – UCB Pharma | |
| Role of automation in maximizing portfolio value – the future is now | |||
| 17:40 | 18:00 | Scott Summerfield – GlaxoSmithKline | |
| Transitioning to an ‘automation-first’ culture in Bioanalysis – our learnings from the last 3 year | |||
| 18:00 | End of Day 1 Q&A | ||
| 11 June 2021 | |||
| 09:45 | Coming online | ||
| 10:00 | 11:20 | Science Café: “How has Covid-19 changed our future? “ | |
| This year, the YSS-OC wants to engage you how Covid-19 impacted our (professional) careers, i.e. things we lost, for good or for bad – things we gained, wanted or unwanted, things we learned about ourselves and our industry. The YSS has prepares a panel discussion for all of you to contribute | |||
| 11:30 | 12:10 | Interactive poster viewing session (5-min poster pitch – posters 1 to 7) | |
| Chair/Moderator/Questions: Mathias/Robin | |||
| 12:10 | 12:40 | Lunch break | |
| 12:50 | 13:30 | Interactive poster viewing session (5-min poster pitch – posters 8 to 14) | |
| Chair/Moderator/Questions: Mathias/Robin | |||
| 13:30 | 14:10 | Was the 6th YSS’ sustainability theme “sustainable”? | |
| 13:30 | 13:50 | Katja Zeiser – Nuvisan | |
| Re-Validation concept for an optimized use of resources – what have we achieved? | |||
| 13:50 | 14:10 | 5-min pitches of “what are WE doing on sustainability?” | |
| Connor Walker (Arcinova – A Quotient Sciences Business), Adam Williams (AstraZeneca), Salvatore Calogero (F. Hoffmann – La Roche) and Ian Dawson (Covance) | |||
| 14:10 | 14:40 | Plenary Feedback from (local or e-) Science Café round tables | |
| 15:00 | 16:20 | Session 5: Novel approaches to ADA/complex assays – how did you overcome them? | |
| Chair/Moderator/Questions: Salvatore/Laura/Tessa | |||
| 15:00 | 15:20 | Hanna Leins – Nuvisan | |
| One for all – development of a generic ADA assay on the Gyrolab Platform | |||
| 15:20 | 15:40 | Christina Aniol-Nielsen – NovoNordisk | |
| Calibration-Free Concentration Analysis for Quantification of Anti-Drug Specific Antibodies in Positive Control Antibodies and in Clinical Samples | |||
| 15:40 | 16:00 | Eugenia Opolka-Hoffmann – F. Hoffmann La Roche (not released for publication) (not released for publication) | |
| The impact of drug/ADA immune complex properties on drug clearance: an in vivo study and the underlying bioanalytical method | |||
| 16:00 | 16:20 | Jayshree Maher – LGC | |
| AlphaLISA – An alternative plaform for immunogencitiy assays? | |||
| 16:40 | 18:20 | Session 6: Biomarkers and CoU: an uphill journey for young scientists? | |
| Chair/Moderator/Questions: Tessa/Adam/Terence | |||
| 16:40 | 16:50 | Philip Timmerman – EBF | |
| Introduction to the session & Background of EBF in relation to Biomarker assay validation | |||
| 16:50 | 17:10 | Kyra Cowan – on behalf of the EBF | |
| Context of Use versus the BMV – why the discussion? | |||
| 17:10 | 17:30 | Léa Costes – Sanquin (not released for publication) | |
| Biomarker assays and context of use: two stories, one success | |||
| 17:30 | 17:50 | Michele Protti – University of Bologna | |
| Pathology biomarkers in animal models of amyotrophic lateral sclerosis: microsampling-based analytical investigation | |||
| 17:50 | 18:20 | Panel discussion: CoU – an uphill journey for young scientists? | |
| 18:20 | Closing Remarks and Adjourn | ||
